Detalhe da pesquisa
1.
Allosteric interactions prime androgen receptor dimerization and activation.
Mol Cell
; 82(11): 2021-2031.e5, 2022 06 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-35447082
2.
Structural insights into BCDX2 complex function in homologous recombination.
Nature
; 619(7970): 640-649, 2023 Jul.
Artigo
em Inglês
| MEDLINE | ID: mdl-37344589
3.
Nuclear RNA Exosome at 3.1 Å Reveals Substrate Specificities, RNA Paths, and Allosteric Inhibition of Rrp44/Dis3.
Mol Cell
; 64(4): 734-745, 2016 11 17.
Artigo
em Inglês
| MEDLINE | ID: mdl-27818140
4.
Substrate discrimination and quality control require each catalytic activity of TRAMP and the nuclear RNA exosome.
Proc Natl Acad Sci U S A
; 118(14)2021 04 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33782132
5.
Exploring new frontiers in prostate cancer research: Report from the 2022 Coffey-Holden prostate cancer academy meeting.
Prostate
; 83(3): 207-226, 2023 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36443902
6.
ERF mutations reveal a balance of ETS factors controlling prostate oncogenesis.
Nature
; 546(7660): 671-675, 2017 06 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-28614298
7.
Substrate selectivity by the exonuclease Rrp6p.
Proc Natl Acad Sci U S A
; 117(2): 982-992, 2020 01 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-31879344
8.
Modulation of androgen receptor DNA binding activity through direct interaction with the ETS transcription factor ERG.
Proc Natl Acad Sci U S A
; 117(15): 8584-8592, 2020 04 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-32220959
9.
Structure of an Rrp6-RNA exosome complex bound to poly(A) RNA.
Nature
; 511(7510): 435-9, 2014 Jul 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-25043052
10.
Exo- and endoribonucleolytic activities of yeast cytoplasmic and nuclear RNA exosomes are dependent on the noncatalytic core and central channel.
Mol Cell
; 48(1): 133-44, 2012 Oct 12.
Artigo
em Inglês
| MEDLINE | ID: mdl-22902556
11.
The Rrp6 C-terminal domain binds RNA and activates the nuclear RNA exosome.
Nucleic Acids Res
; 45(2): 846-860, 2017 01 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-27899565
12.
Cryo-EM structures of Uba7 reveal the molecular basis for ISG15 activation and E1-E2 thioester transfer.
Nat Commun
; 14(1): 4786, 2023 08 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-37553340
13.
Clearing the air: Uniquely engaging furin as an approach to cystic fibrosis therapy.
Cell Chem Biol
; 29(6): 927-929, 2022 06 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-35714591
14.
Crystal structures reveal catalytic and regulatory mechanisms of the dual-specificity ubiquitin/FAT10 E1 enzyme Uba6.
Nat Commun
; 13(1): 4880, 2022 08 19.
Artigo
em Inglês
| MEDLINE | ID: mdl-35986001
15.
Characterization of placental cholesterol transport: ABCA1 is a potential target for in utero therapy of Smith-Lemli-Opitz syndrome.
Hum Mol Genet
; 17(23): 3806-13, 2008 Dec 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-18775956
16.
Supplemental dietary inulin influences expression of iron and inflammation related genes in young pigs.
J Nutr
; 139(11): 2018-23, 2009 Nov.
Artigo
em Inglês
| MEDLINE | ID: mdl-19776179
17.
Structure and reconstitution of yeast Mpp6-nuclear exosome complexes reveals that Mpp6 stimulates RNA decay and recruits the Mtr4 helicase.
Elife
; 62017 07 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-28742025
18.
Structure and Activities of the Eukaryotic RNA Exosome.
Enzymes
; 31: 53-75, 2012.
Artigo
em Inglês
| MEDLINE | ID: mdl-27166440